{"type":"standard","title":"Fabomotizole","displaytitle":"Fabomotizole","namespace":{"id":0,"text":""},"wikibase_item":"Q2090655","titles":{"canonical":"Fabomotizole","normalized":"Fabomotizole","display":"Fabomotizole"},"pageid":25162841,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/f/ff/%D0%A4%D0%B0%D0%B1%D0%BE%D0%BC%D0%BE%D1%82%D0%B8%D0%B7%D0%BE%D0%BB.png/330px-%D0%A4%D0%B0%D0%B1%D0%BE%D0%BC%D0%BE%D1%82%D0%B8%D0%B7%D0%BE%D0%BB.png","width":320,"height":350},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/f/ff/%D0%A4%D0%B0%D0%B1%D0%BE%D0%BC%D0%BE%D1%82%D0%B8%D0%B7%D0%BE%D0%BB.png","width":1091,"height":1194},"lang":"en","dir":"ltr","revision":"1250024203","tid":"f9e4b886-8518-11ef-b3ff-4b1b1aba9d13","timestamp":"2024-10-08T01:59:39Z","description":"Anxiolytic drug","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Fabomotizole","revisions":"https://en.wikipedia.org/wiki/Fabomotizole?action=history","edit":"https://en.wikipedia.org/wiki/Fabomotizole?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Fabomotizole"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Fabomotizole","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Fabomotizole","edit":"https://en.m.wikipedia.org/wiki/Fabomotizole?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Fabomotizole"}},"extract":"Fabomotizole is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety.","extract_html":"
Fabomotizole is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety.
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{"slip": { "id": 202, "advice": "Never waste an opportunity to tell someone you love them."}}
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